Exostema caribaeum, commonly known as princewood, Caribbean princewood, or Jesuit bark, is a species of flowering plant in the family Rubiaceae. It is a shrub or tree with papery leaves, white flowers, and brown capsule fruits.

Exostema caribaeum is native to forests in the United States, the Caribbean, and central America. The species was described in 1760. In 2018, the IUCN listed it as of Least Concern. It is used for medicine, timber, and horticulture.