Cucumis melo, also known as melon or true melon, is a species of Cucumis that has been developed into many cultivated varieties. The fruit is a pepo. The flesh is either sweet or bland, with or without an aroma, and the rind can be smooth (such as honeydew), ribbed (such as European cantaloupe), wrinkled (such as Casaba melon) or netted (such as American cantaloupe). The species is sometimes referred to as muskmelon. However, there is no consensus about the usage of this term, as it can also be used as a specific name for the musky netted-rind American cantaloupe, or as a generic name for any sweet-flesh variety such the inodorous smooth-rind honeydew melon.

Melon were domesticated four times independently. Research has revealed that seeds and rootstocks were among the goods traded along the caravan routes of the Ancient World. Some botanists consider melons native to the Levant and Egypt, while others place their origin in Iran, India or Central Asia. Still others support an African origin; in modern times, wild melons can still be found in some African countries.