Asclepias viridiflora; also known as green comet milkweed, green-flower milkweed, and green milkweed; is a species of milkweed (Asclepias). The plant is located in the eastern and central United States, ranging between Connecticut to Georgia and Arizona to Montana, and is also in southern Canada and northern Mexico. The Latin epithet viridiflora translates as "green-flowered".

Asclepias viridiflora is an erect to ascending herb up to 50 cm tall, with greenish-white flowers. The pods lack the warts and tubercules common on other species of Asclepias. It grows in moist to dry shaded roadsides, fields, and prairies.